Painkillers, or, as they are called in medicine - analgesics, are designed to identify, and most importantly, eliminate the causes of pain. Painkillers are divided into narcotic, addictive with prolonged use, and non-narcotic, not affecting the central nervous system and not addictive. In all the variety of analgesics in a short review, we will consider the most effective drugs, and choose the most powerful pain medication.
TheBiggest.ru strongly discourages self-medication! It can be life threatening.
Narcotic analgesics
Let's start the rating with opioid or narcotic painkillers. Strong painkillers of this group are used only in case of acute and intolerable pain in patients.
1
Buprenorphine
A very strong painkiller in the form of a white crystalline powder, which is poorly soluble in water, and therefore alcohol solutions are used.
Quickly relieves pain after surgery. It is prescribed for operated oncological patients, patients after heart operations and renal colic, as well as for severe burns.
It is not recommended to use during pregnancy, head injuries. As well as people with a low threshold of physical dependence when using opioid drugs.
2
Butorphanol
White crystalline substance, easily soluble in water, also refers to opioid pain relievers.
Easily relieves moderate and severe pain syndrome of various origins, and is actively used in postoperative rehabilitation.
It should be prescribed with caution, as it has many side effects, an overdose can enter the patient into a coma, and the lethal dose is 50 mg / l.
3
Morphine
A powerful pain reliever will relieve pronounced pain syndrome with myocardial infarction, angina pectoris and injuries of various severity.
They are prescribed for patients with cancer, with severe injuries, when nerve damage occurs in an unfinished area of the body. It is widely used in the postoperative period.
During use, dizziness, asthenia may be felt, the patient may experience anxiety. Pregnant and lactating mothers are used only in case of emergency.
4
Codeine
Natural narcotic analgesic from a well-known group of opiate receptor agonists, which anesthetizes by acting on the central nervous system.
The drug changes the emotional perception of pain, therefore it is prescribed with great care, and only in cases of removal of intolerable pain syndrome. Easily relieves pain in injuries, cancer, bouts of unproductive cough.
It is not recommended for hypersensitivity, bronchial asthma, as well as for impaired renal and hepatic function, and, naturally, during pregnancy.
5
Promedol
Anesthetics for bone fractures are also divided into narcotic and non-narcotic ones, and the highly effective Promedol drug belongs to the first group.
Since this is a narcotic analgesic, it cannot be purchased without a prescription, but it is used mainly for numerous fractures, when soft tissue rupture and damage to internal organs occur.
The main substance in the composition of the drug trimeperidine is usually easily tolerated by patients, but is not recommended for respiratory depression and hypersensitivity.
6
Tramadol
A psychotropic analgesic from the opioid group has a strong analgesic activity, and most importantly it has a very fast and long-lasting effect.
Loses morphine, because I use large doses for pain relief in the postoperative period. The action occurs after 20 minutes and continues to operate for 6 hours.
It was opened in 1962 by a German company, and today it is widely used in medicine. According to statistics, it has been prescribed since opening 70 million patients.
7
Nalbufin
Another strong opioid analgesic that was officially allowed to be used on the territory of Russia in April 2013, and in Ukraine it is part of the first-aid kit of an Emergencies Ministry physician.
When administered intramuscularly, its effect is comparable to morphine, and the active substance begins to act 30-40 minutes after injection. This is a relatively new drug, because its side effects continue to be investigated.
The drug is contraindicated in patients with respiratory depression, as in such patients severe asthma attacks may begin.
8
Tebain
The name of the medicine was given to the ancient Egyptian name of the city of Thebes, in which opium was produced during the period of the Old Kingdom.
It is practically not used for therapeutic purposes, since the substance has high toxicity. In fact, this is not a drug, but a convulsive poison. But it is used for the production of many drugs with analgesic effects.
Thebaine is obtained from thebaine resin, and in opium it is 0.2 percent.
Non-narcotic painkillers
It is difficult to choose the most effective analgesic among the whole variety, and with experience, each individually, on the advice of a doctor, dwells on a particular drug, and, of course, depending on the situation.
1
Citramon
The most popular analgesic in the post-Soviet space, which relieves pain, has an antipyretic and anti-inflammatory effect, and also thins the blood.
Blood thinning drugs are used to avoid blood clots, and citramon in this series, though not the most effective, but effective drug.
The drug with the initial composition has not been produced for a long time, and the name was left more as a reminder of the effectiveness and low price of the medicine, but the brand really works. Due to the many side effects in the west, it is practically not used.
2
Nurofen
Our list continues with the anti-inflammatory drug, the most popular treatment among non-steroid drugs, and today, perhaps, the best pain medication.
The action is quite simple, Nurofen simply blocks pain mediators, leading to a quick analgesic effect. The synthesis of prostaglandids stops, and the pain goes away.
Doctors recommend using it also for headaches and neuralgia. It can also be used as an antipyretic. You can only take the strongest painkillers when you are 6 years old.
3
Ketorol
The drug with a pronounced analgesic effect is available in the form of tablets, ampoules for injection, as well as a gel.
In addition to analgesia, it also has anti-inflammatory effects, and may slightly reduce fever. It is especially effective for fractures of the limbs, when it is necessary to immediately anesthetize the pain syndrome.
Anesthetic injections for fractures are the most effective method, since the medicine immediately dissolves in the body, and the release of ketorol in the form of ampoules only adds to its popularity.
4
Askofen
Askofen also belongs to effective medicines, and its components are synergistic. It is usually prescribed for mild or moderate pain, but it acts quickly, which is why it is quite popular.
Do not use ascofen with paracetamol and medicines containing acetylsalicylic acid.
5
Nalgesin
An effective anti-inflammatory drug is a crystalline powder that does not dissolve in water, and the structure is destroyed at 40 ° C.
The medicine is released in tablets, rectal ampoules, and veterinary medicine is used in a liquid state. Prescribe to take one tablet 2 times a day, drinking plenty of water.
The advantage of the drug is a fairly wide spectrum of action, and during use the pain and heat disappear, and most importantly, further synthesis of prostaglandins is prevented.
6
Ibuklin
This potent drug is a complex painkiller, and is based on the synthesis of ibuprofen and paracetamol.
It has a fairly wide spectrum of action, but it best eliminates headaches, toothaches, and is used for injuries and arthritis. It can be used to lower the temperature.
Do not use for children under 12 years old, pregnant women, hypersensitive people, or those with stomach ulcers.
7
Dexalgin
Nonsteroidal anti-inflammatory and antirheumatic drug, created on the basis of propionic acid.
Quickly relieves light and severe pain, affecting the synthesis of prostaglandins, relieving inflammation and lowering fever. It is widely used for headaches and toothaches, for menstrual pains, as well as relieving pain during bruises or injuries.
Quite an effective drug, but it is not recommended to use Dexalgin along with other medicines, as well as people who are allergic to the active substance contained in the medicine.
8
Diclofenac
An analgesic was created in 1966, and is included in the group of non-steroidal drugs, created on the basis of phenylacetic acid derivatives.
After recent studies, Diclofenac has been expanded significantly. Today it is actively used in surgery, traumatology. The drug received good reviews from sports doctors as a good pain medication.
After use, you may feel slight dizziness, nausea, and very rarely can the skin react, which is covered with a small rash.
9
Spazmalgon
A comprehensive and effective analgesic from the NSAID group, which contains an antispasmodic and enhancing the analgesic effect of the components.
It acts quickly enough, due to inhibition of prostaglandins, as well as reducing the release of calcium into the muscles. One of the advantages can be called what can be used for diseases of the gastrointestinal tract.
Spazmalgon is popular in the post-Soviet space, but has not been produced in the USA, Western Europe, Japan and Australia for more than 30 years.
10
Ketanov
According to reviews and experts, the most powerful painkiller, included in the group of vital and essential medicines for life and health.
The active component of Ketorolac, which is part of the drug, effectively blocks the synthesis of prostagladins, relieves inflammation and regulates the body's thermoregulation.
Among the advantages, fast action is noted, literally 15 minutes after ingestion. And among the shortcomings is called the fact that the drug does not eliminate chronic pain.
Analogues of painkillers
We conclude our review with a list of substitutes that are similar in composition and principle of action, but differ sharply in price from their expensive counterparts.
1
Ibuprofen
A non-steroidal anti-inflammatory drug, created on the basis of propionic acid, relieves pain well, and also has antipyretic properties.
It was first synthesized in 1962 by Stuart Adams and John Nicholson. Perfectly reduces pain due to the large number of pharmacological preparations that make up its composition.
It is a substitute for Nurofen, and is almost 5 times cheaper than its counterpart.
2
Paracetamol
In Western countries, this drug is known under the name "Acetaminophen", and is used to relieve pain and reduce heat.
A non-narcotic analgesic was introduced into medical practice at the end of the 19th century, and it quickly gained popularity as an inexpensive and very effective remedy.
It perfectly relieves pain and fever syndrome, and it is recommended to take it with plenty of fluids. Today, this is perhaps the best way to relieve headaches.
3
Meloxicam
The non-steroidal anti-inflammatory drug belongs to the group of oxycams, and is dispensed in tablets.
Like many drugs of the oxycam group, which is close to pyroxocam, it has anti-inflammatory, antipyretic and analgesic effects, and also a rather cheap pain medication.
The composition includes lactose, so it is not recommended for people who have lactose intolerance, as well as who have a deficiency of glucose-galactose malabsorption.
Today, effective painkillers can be bought at any pharmacy, but remember, before you take anything, be sure to consult a specialist. Naturally, I want to remove the pain as quickly as possible, but any self-medication can harm, because every drug has side effects and contraindications.
So we learned what painkillers are, but we remind you that the information in the article is provided for informational purposes only.
Article author: Valery Skiba